Fig. 1

Box-and-whisker plots of biochemical parameters. L0 baseline values, L6m after 6 months of L, L12m after 12 m of L, L+T0 before start of L+T, L+T6m after 6 months of L+T, L+T12m after 12 months of L+T. a Hemoglobin (g/dL, multiply by 10 for SI units: g/L); b hematocrit (%, multiply by 0,01 for SI units: proportion of 1.0); c AST (U/L, multiply by 0.0167 for SI units: μkat/L); d ALT (U/L, multiply by 0.0167 for SI units: μkat/L); e HDL (mg/dL, multiply by 0.0259 for SI units: mmol/L); f LDL (mg/dL, multiply by 0.0259 for SI units: mmol/L); g creatinine (mg/dL, multiply by 88.4 for SI units: μmol/L); h sex hormone-binding globulin (nmol/L); i luteinizing hormone (U/L); j estradiol (ng/L, multiply by 3.671 for SI units: pmol/L); k testosterone (ng/dL, multiply by 0.0347 for SI units: nmol/L); l free testosterone (ng/dL, multiply by 34.7 for SI units: pmol/L). L lynestrenol monotherapy; L+T lynestrenol and testosterone esters combination therapy, AST/ALT aspartate/alanine amino transferase, HDL/LDL high/low density lipoprotein