Table 1 Questions reviewers should consider when evaluating SABV
From: Evaluating sex as a biological variable in preclinical research: the devil in the details
Research approach for SABV • Clarity of the research question. • Clarity of rationale for the research approach and methodology. • Appropriateness of the research design. • Appropriateness of the research methods. • Feasibility of the research approach. • Anticipation of difficulties that may be encountered in the research and plans for management. • Quality and appropriateness of SABV. • Justification for a single-sex study. • Evidence that the research question incorporates SABV. • Potential for the research to add value to the current state of knowledge on a given topic that has potential to, but has not yet fully elucidated the impact of sex on biological mechanisms, pathophysiology or translational science. Impact of research incorporating SABV • Potential for a significant contribution to the improvement of women and men’s health, the health of boys and girls, or the health of gender-diverse persons. • Appropriateness and adequacy of the proposed plan for knowledge dissemination and exchange. |