Skip to main content

Table 3 MSY altered phenotypes with differences in male to female rat strains

From: The phenotypic impact of the male-specific region of chromosome-Y in inbred mating: the role of genetic variants and gene duplications in multiple inbred rat strains

Phenotype Rat treatment Consomic with significant change Male to female BN significant Male to female FHH significant Male to female SS significant
Plasma lymph abs (E3) 12 % O2, 0.4 % salt, male FHH-YBN/Mcwi No Yes
Plasma segmented neutrophils (E3) 12 % O2, 0.4 % salt, male FHH-YBN/Mcwi No Yes
Plasma mean corpuscular hemoglobin content (pg) 12 % O2, 0.4 % salt, male FHH-YBN/Mcwi Yes No
Plasma mean corpuscular volume (fL) 12 % O2, 0.4 % salt, male FHH-YBN/Mcwi Yes No
Plasma red blood cell (E6/μL) 21 % O2, 0.4 % salt, male FHH-YBN/Mcwi Yes No
Pre-ischemic heart wet weight (g) 12 % O2, 0.4 % salt, male FHH-YBN/Mcwi Yes No
Pre-ischemic heart wet weight (g) 21 % O2, 0.4 % salt, male FHH-YBN/Mcwi Yes No
Pre-ischemic left ventricle developed pressure (mmHg) 12 % O2, 0.4 % salt, male FHH-YBN/Mcwi Yes No
Pre-ischemic left ventricle systolic pressure (mmHg) 12 % O2, 0.4 % salt, male FHH-YBN/Mcwi Yes No
Methacholine ED50 (mg/kg) 21 % O2, 0.4 % salt, male FHH-YBN/Mcwi Yes No
Dilator response to acetylcholine EC50 (E-7 mole) 21 % O2, 0.4 % salt, male FHH-YBN/Mcwi Yes No
Dilator response to acetylcholine Log EC50 (Log molar) 21 % O2, 0.4 % salt, male FHH-YBN/Mcwi Yes No
Plasma alk phos (U/L) 21 % O2, 0.4 % salt, male FHH-YBN/Mcwi Yes Yes
Plasma globulin (g/dL) 21 % O2, 0.4 % salt, male FHH-YBN/Mcwi Yes Yes
Plasma hematocrit (%) 21 % O2, 0.4 % salt, male FHH-YBN/Mcwi Yes Yes
Plasma hemoglobin (g/dL) 21 % O2, 0.4 % salt, male FHH-YBN/Mcwi Yes Yes
Plasma phosphorus (mg/dL) 21 % O2, 0.4 % salt, male FHH-YBN/Mcwi Yes Yes
Plasma total protein (g/dL) 21 % O2, 0.4 % salt, male FHH-YBN/Mcwi Yes Yes
Plasma white blood cell count (E3/μL) 12 % O2, 0.4 % salt, male FHH-YBN/Mcwi Yes Yes
Ischemic peak contracture (mmHg) 12 % O2, 0.4 % salt, male FHH-YBN/Mcwi Yes Yes
Body weight (kg) 12 % O2, 0.4 % salt, male FHH-YBN/Mcwi Yes Yes
Body weight (kg) 12 % O2, 0.4 % salt, male FHH-YBN/Mcwi Yes Yes
Body weight (kg) 21 % O2, 0.4 % salt, male FHH-YBN/Mcwi Yes Yes
Lung dry wt (g)/body wt. (kg) ratio (g/kg) 21 % O2, 0.4 % salt, male FHH-YBN/Mcwi Yes Yes
Hematocrit (%) 21 % O2, 0.4 % salt, male FHH-YBN/Mcwi Yes Yes
Rt ventricle/left ventricle weight ratio (w/w ratio) 12 % O2, 0.4 % salt, male FHH-YBN/Mcwi Yes Yes
Body weight 21 % O2, 0.4 % salt, male FHH-YBN/Mcwi Yes Yes
r @flow = 100 ml/min/g (mmHg × min × kg × ml−1) 21 % O2, 0.4 % salt, male SS-YBN/Mcwi No Yes
Plasma red blood cell (E6/μL) 21 % O2, 0.4 % salt, male SS-YBN/Mcwi Yes No
Dilator response to acetylcholine EC50 (E-7 mole) 21 % O2, 0.4 % salt, male SS-YBN/Mcwi Yes No
Dilator response to acetylcholine Log EC50 (Log molar) 21 % O2, 0.4 % salt, male SS-YBN/Mcwi Yes No
Plasma calcium (mg/dL) 21 % O2, 0.4 % salt, male SS-YBN/Mcwi Yes Yes
Plasma globulin (g/dL) 21 % O2, 0.4 % Salt, Male SS-YBN/Mcwi Yes Yes
Plasma globulin (g/dL) 12 % O2, 0.4 % salt, male SS-YBN/Mcwi Yes Yes
Plasma hematocrit (%) 12 % O2, 0.4 % salt, male SS-YBN/Mcwi Yes Yes
Plasma hemoglobin (g/dL) 21 % O2, 0.4 % salt, male SS-YBN/Mcwi Yes Yes
Plasma hemoglobin (g/dL) 12 % O2, 0.4 % salt, male SS-YBN/Mcwi Yes Yes
Plasma mono abs (E3) 21 % O2, 0.4 % salt, male SS-YBN/Mcwi Yes Yes
Plasma potassium (mmol/L) 21 % O2, 0.4 % salt, male SS-YBN/Mcwi Yes Yes
Plasma red blood cell (E6/μL) 12 % O2, 0.4 % Salt, Male SS-YBN/Mcwi Yes Yes
Plasma total protein (g/dL) 12 % O2, 0.4 % salt, male SS-YBN/Mcwi Yes Yes
Ischemic time to onset of contracture (s) 12 % O2, 0.4 % salt, male SS-YBN/Mcwi Yes Yes
Ischemic time to peak contracture (s) 12 % O2, 0.4 % salt, male SS-YBN/Mcwi Yes Yes
Pre-ischemic heart rate (beats/min) 12 % O2, 0.4 % salt, male SS-YBN/Mcwi Yes Yes
Pre-ischemic heart wet weight (g) 12 % O2, 0.4 % salt, male SS-YBN/Mcwi Yes Yes
Body weight (kg) 12 % O2, 0.4 % salt, male SS-YBN/Mcwi Yes Yes
Body weight (kg) 12 % O2, 0.4 % salt, male SS-YBN/Mcwi Yes Yes
Lung dry wt (g)/body wt. (kg) ratio (g/kg) 12 % O2, 0.4 % salt, male SS-YBN/Mcwi Yes Yes
Hematocrit (%) 21 % O2, 0.4 % salt, male SS-YBN/Mcwi Yes Yes
Hematocrit (%) 12 % O2, 0.4 % salt, male SS-YBN/Mcwi Yes Yes
Body weight (kg) 21 % O2, 0.4 % salt, male SS-YBN/Mcwi Yes Yes
Rectal temperature after hypercapnia (°C) 21 % O2, 0.4 % salt, male SS-YBN/Mcwi Yes Yes
% maximum relaxation acetylcholine (%) 21 % O2, 0.4 % salt, male SS-YBN/Mcwi Yes Yes