Combined | Female | Male | |||
---|---|---|---|---|---|
n = 416 | n = 293 | ||||
n | Mean (SD) or n (%) | Mean (SD) or n (%) | Mean (SD) or n (%) | p value | |
Age, years | 709 | 65.4 (9) | 64.6 (8.9) | 66.5 (9) | 0.05 |
Weight, kg | 709 | 87.7 (19.1) | 81.3 (17.5) | 96.8 (17.5) | <.0001 |
BMI, kg/m2 | 709 | 31 (5.9) | 30.9 (6.5) | 31 (5) | 1.00 |
SBP, mmHg | 705 | 149 (25) | 150 (25) | 147 (25) | 0.09 |
DBP, mmHg | 705 | 84 (11) | 82 (11) | 86 (11) | 0.95 |
Serum creatinine, mg/dL | 612 | 0.9 (0.2) | 0.8 (0.2) | 1.0 (0.2) | <.0001 |
eGFRCys, ml/min/1.73 m2 | 601 | 85.6 (24.7) | 87.9 (25.8) | 82.5 (22.8) | 0.02 |
Diabetes status | 625 | 0.21 | |||
Yes | 87 (13.9) | 45 (12.4) | 42 (16.1) | ||
No | 538 (86.1) | 319 (87.6) | 219 (83.9) | ||
Blood glucose, mg/dL | 612 | 96.1 (22.9) | 94.8 (23.0) | 98.0 (22.7) | 0.24 |
Dietary measures | |||||
Oxalate, mg/day | 511 | 215.8 (126.3) | 217.9 (121.3) | 212.9 (133.3) | 0.64 |
Animal protein, g/day | 521 | 52.9 (25.4) | 48.9 (21.4) | 58.7 (29.4) | <.0001 |
Sodium, mg/day | 521 | 3140 (1407) | 2947 (1313) | 3419 (1491) | <0.0001 |
Water intake, g | 521 | 2950 (1119) | 3004 (1050) | 2873 (1211) | <0.0001 |
Total protein, g/day | 521 | 80.4 (33.9) | 75.5 (29.9) | 87.3 (37.9) | <0.0001 |
Sucrose, g/day | 519 | 37.2 (20.7) | 38 (20.4) | 36 (21.1) | 0.34 |
Calcium, mg/day | 521 | 1059 (542) | 1060 (517) | 1057 (578) | <0.0001 |
Diuretic use | |||||
Loop | 709 | 0.61 | |||
Yes | 35 (4.9) | 22 (5.3) | 13 (4.4) | ||
No | 674 (95.1) | 394 (94.7) | 280 (95.6) | ||
Thiazide | 709 | 0.99 | |||
Yes | 259 (36.5) | 152 (36.5) | 107 (36.5) | ||
No | 450 (63.5) | 264 (63.5) | 186 (63.5) | ||
Urinary traits | |||||
Urine osmolality, mOsm/kg | 709 | 511.3 (188.6) | 456.1 (165.7) | 589.8 (191.7) | <0.0001 |
Urine volume, mL/day | 709 | 1971.1 (690.77) | 1967.65 (675.26) | 1975.99 (713.36) | 0.8743 |
Total mOsm/day | 709 | 932 (314) | 829 (257) | 1078 (329) | <0.0001 |
Urine sodium, mmol/day | 705 | 143 (58) | 123 (48) | 170 (61) | <0.0001 |
Urine potassium, mmol/day | 709 | 59 (23) | 52 (19) | 70 (23) | <0.0001 |
Electrolyte contribution to urine osmole load, mmol/day | 705 | 403 (145) | 349 (116) | 478 (148) | <0.0001 |
Urea contribution to urine osmole load, mmol/day | 705 | 523 (242) | 476 (212) | 591 (264) | <0.0001 |