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Table 1 Descriptive statistics

From: Key influence of sex on urine volume and osmolality

  

Combined

Female

Male

 
   

n = 416

n = 293

 
 

n

Mean (SD) or n (%)

Mean (SD) or n (%)

Mean (SD) or n (%)

p value

Age, years

709

65.4 (9)

64.6 (8.9)

66.5 (9)

0.05

Weight, kg

709

87.7 (19.1)

81.3 (17.5)

96.8 (17.5)

<.0001

BMI, kg/m2

709

31 (5.9)

30.9 (6.5)

31 (5)

1.00

SBP, mmHg

705

149 (25)

150 (25)

147 (25)

0.09

DBP, mmHg

705

84 (11)

82 (11)

86 (11)

0.95

Serum creatinine, mg/dL

612

0.9 (0.2)

0.8 (0.2)

1.0 (0.2)

<.0001

eGFRCys, ml/min/1.73 m2

601

85.6 (24.7)

87.9 (25.8)

82.5 (22.8)

0.02

Diabetes status

625

   

0.21

 Yes

 

87 (13.9)

45 (12.4)

42 (16.1)

 

 No

 

538 (86.1)

319 (87.6)

219 (83.9)

 

Blood glucose, mg/dL

612

96.1 (22.9)

94.8 (23.0)

98.0 (22.7)

0.24

Dietary measures

     

 Oxalate, mg/day

511

215.8 (126.3)

217.9 (121.3)

212.9 (133.3)

0.64

 Animal protein, g/day

521

52.9 (25.4)

48.9 (21.4)

58.7 (29.4)

<.0001

 Sodium, mg/day

521

3140 (1407)

2947 (1313)

3419 (1491)

<0.0001

 Water intake, g

521

2950 (1119)

3004 (1050)

2873 (1211)

<0.0001

 Total protein, g/day

521

80.4 (33.9)

75.5 (29.9)

87.3 (37.9)

<0.0001

 Sucrose, g/day

519

37.2 (20.7)

38 (20.4)

36 (21.1)

0.34

 Calcium, mg/day

521

1059 (542)

1060 (517)

1057 (578)

<0.0001

Diuretic use

     

 Loop

709

   

0.61

  Yes

 

35 (4.9)

22 (5.3)

13 (4.4)

 

  No

 

674 (95.1)

394 (94.7)

280 (95.6)

 

 Thiazide

709

   

0.99

  Yes

 

259 (36.5)

152 (36.5)

107 (36.5)

 

  No

 

450 (63.5)

264 (63.5)

186 (63.5)

 

Urinary traits

     

 Urine osmolality, mOsm/kg

709

511.3 (188.6)

456.1 (165.7)

589.8 (191.7)

<0.0001

 Urine volume, mL/day

709

1971.1 (690.77)

1967.65 (675.26)

1975.99 (713.36)

0.8743

 Total mOsm/day

709

932 (314)

829 (257)

1078 (329)

<0.0001

 Urine sodium, mmol/day

705

143 (58)

123 (48)

170 (61)

<0.0001

 Urine potassium, mmol/day

709

59 (23)

52 (19)

70 (23)

<0.0001

 Electrolyte contribution to urine osmole load, mmol/day

705

403 (145)

349 (116)

478 (148)

<0.0001

 Urea contribution to urine osmole load, mmol/day

705

523 (242)

476 (212)

591 (264)

<0.0001

  1. p values were testing for sex differences, using linear mixed models to account for sibships. Water intake includes water from food consumption
  2. SD standard deviation, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, eGFR estimated glomerular filtration rate (cystatin calculation)