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Table 1 Biophysical measures in CA1 pyramidal neurons that were not altered by the high-fat diet (HFD) in young adult male and female rats

From: High-fat diet impairs spatial memory and hippocampal intrinsic excitability and sex-dependently alters circulating insulin and hippocampal insulin sensitivity

  Rats (n) Neurons (n) Input resistance (MΩ) Sag (mV) Resting potential (mV)
Control male      
 aCSF 22 23 81.0 ± 2.4 8.3 ± 0.6 −70.2 ± 0.3
 Insulin   15 85.9 ± 3.0 10.2 ± 0.1 −66.0 ± 1.3
HFD male      
 aCSF 14 24 66.7 ± 2.3 8.1 ± 0.6 −67.5 ± 0.6
 Insulin   13 64.3 ± 3.5 8.9 ± 1.0 −68.7 ± 0.4
Control female      
 aCSF 7 14 59.6 ± 3.4 4.6 ± 0.8 −71.6 ± 0.4
 Insulin   8 53.6 ± 1.2 7.1 ± 0.9 −66.7 ± 0.6
HFD female      
 aCSF 14 20 85.5 ± 4.8 6.5 ± 0.5 −70.3 ± 0.4
 Insulin   9 87.0 ± 6.9 10.1 ± 2.2 −63.3 ± 1.7