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Fig. 4 | Biology of Sex Differences

Fig. 4

From: Sex and estrogens alter the action of glucagon-like peptide-1 on reward

Fig. 4

Effect of central estrogen blockade on the actions of Ex4 on peanut butter consumption or chow intake is not divergent between the sexes. No significant changes in peanut butter consumption were observed in males (a), but a significant reduction in consumption was noted in females after injection of Ex4 or Ex4 and ICI (c). Ex4 reduced chow intake in both males and females (b, d). This reduction was attenuated by simultaneous ICI treatment only in females. Chow and peanut butter consumption are displayed in grams. Data are expressed as mean ± SEM. n = 10 (females) and 9 (males) per treatment group for peanut butter measurement and n = 10 (females) and 18 (males) per treatment group for chow intake. *p < 0.05, ***p < 0.001

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