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Fig. 6 | Biology of Sex Differences

Fig. 6

From: Perinatal testosterone exposure is critical for the development of the male-specific sexually dimorphic gastrin-releasing peptide system in the lumbosacral spinal cord that mediates erection and ejaculation

Fig. 6

Masculinization of the spinal GRP system in female neonates exposed to androgens. Representative photomicrographs of female neonates treated with 5α-dihydrotestosterone (DHT). Neonatal administration of DHT increased the number and intensity of GRP-immunoreactive neurons (left panels). Immunohistochemical analysis of GRP (green) and nNOS (magenta) showing significantly increased intensity of GRP-immunoreactive fibers in the SPN induced by neonatal administration of DHT. Arrowheads indicate possible GRP-positive cell bodies. Scale bars 100 μm, left panel; 50 μm, right panel

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Biology of Sex Differences

ISSN: 2042-6410

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