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Fig. 5 | Biology of Sex Differences

Fig. 5

From: Perinatal testosterone exposure is critical for the development of the male-specific sexually dimorphic gastrin-releasing peptide system in the lumbosacral spinal cord that mediates erection and ejaculation

Fig. 5

Semi-quantitative analysis of the effects of the androgen surge on the developing spinal GRP system of males. Castrating rats at birth (ORX) decreased the number and intensity of GRP-immunoreactive neurons in the spinal cord during adulthood. These effects were prevented if the castrates were treated with testosterone propionate (ORX + TP) immediately after castration. Number of GRP neurons (a) and intensity of GRP-immunoreactive fibers (b) in the lumbosacral spinal cord. * P < 0.01 vs. control; P < 0.01 vs. ORX

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