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Fig. 2 | Biology of Sex Differences

Fig. 2

From: Perinatal testosterone exposure is critical for the development of the male-specific sexually dimorphic gastrin-releasing peptide system in the lumbosacral spinal cord that mediates erection and ejaculation

Fig. 2

Flutamide administered to neonatal male rats demasculinizes the spinal GRP system. Flutamide decreased the number and intensity of GRP-immunoreactive neurons (left panels). Immunohistochemical analysis of the expression of GRP (green) and neuronal nitric oxide synthase (magenta) show a decrease in the intensity of GRP-immunoreactive fibers in the SPN. Arrowheads indicate possible GRP-positive cell bodies. Scale bars 100 μm, left panel; 50 μm, right panel

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Biology of Sex Differences

ISSN: 2042-6410

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