Skip to main content
Fig. 4 | Biology of Sex Differences

Fig. 4

From: Spatial sexual dimorphism of X and Y homolog gene expression in the human central nervous system during early male development

Fig. 4

Padlock hybridization with ACTB, PCDH11X/Y and NLGN4X/Y. a, b. Male MO sections simultaneously hybridized with one padlock probe for ACTB, five probes for PCDH11X and five for PCDH11Y. a, b The same region of the section with staining for nuclei and ACTB (a) and PCDH11X (cyan) and PCDH11Y (red) (b). Most stained cells express either PCDH11X or PCDH11Y. Rarely, some cells express both X and Y transcripts (marked with arrows). c, d Male MO section simultaneously hybridized with one padlock probe for ACTB, four probes for NLGN4X and four for NLGN4Y. Nuclei and ACTB staining are shown in c, and NLGN4X (cyan) and NLGN4Y (red) staining in d. e Male SC section simultaneously hybridized with five probes for PCDH11X (cyan), five for PCDH11Y (blue), four probes for NLGN4X (red) and four for NLGN4Y (purple)

Back to article page