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Table 1 mRNA levels of puberty-related genes in rostral (HTr) and medial basal hypothalamus (MBH)

From: Interaction between neonatal maternal deprivation and serum leptin levels on metabolism, pubertal development, and sexual behavior in male and female rats

  Sex CoVh CoLept MDVh MDLept
Kiss1 HTr M 100 ± 8.0 95.6 ± 16.0 109.7 ± 9.0 114.4 ± 25.0
F 438.4 ± 146.2a 467.1 ± 109.8a 506.8 ± 84.3a 319.2 ± 45.6a
Kiss1 MBH M 100 ± 8.0 126.3 ± 12.9 116.4 ± 8.7 128.0 ± 19.5
F 192.0 ± 22.2a 185.5 ± 33.6a 172.1 ± 18.8a 215.6 ± 31.5a
Gpar54 HTr M 100 ± 9.2 95.4 ± 6.6 102.5 ± 6.3 92.2 ± 12.3
F 123.0 ± 12.2 100.8 ± 6.3 100.8 ± 6.1 94.8 ± 4.9
Gpar54 MBH M 100 ± 8.0 99.4 ± 3.9 103.9 ± 5.0 111.9 ± 9.6
F 119.9 ± 4.1 104.0 ± 5.5 112.6 ± 16.0 104.0 ± 7.3
Rfrp HTr M 100 ± 43.6 17.0 ± 3.4 31.7 ± 6.4 39.8 ± 15.8
F 49.3 ± 11.4 39.0 ± 12.3 88.6 ± 26.1 90.8 ± 38.7
Rfrp MBH M 100 ± 12.9 107.8 ± 13.8 95.1 ± 10.8 117.2 ± 13.7
F 104.9 ± 7.0 110.5 ± 18.6 112.0 ± 11.5 109.9 ± 6.0
Nprffr1 HTr M 100 ± 8.1 110.0 ± 5.4 100.1 ± 4.0 106.7 ± 8.9
F 107.1 ± 11.2 119.7 ± 4.7 98.3 ± 5.6 94.0 ± 12.1
Nprffr1 MBH M 100 ± 12.8 129.2 ± 7.9 110.6 ± 8.2 115.9 ± 7.5
F 107.4 ± 5.1 116.1 ± 10.7 100 ± 5.8 108.6 ± 15.4
  1. Data are expressed as mean ± SEM and normalized to control (Co) values. Co and maternal deprivation (MD) male (M) and female (F) rats with leptin treatment (Lept) or vehicle (Vh) from postnatal day (PND) 9 to PND13. n = 5–6 per experimental group
  2. aMain effect of sex; three-way ANOVA
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