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Fig. 7 | Biology of Sex Differences

Fig. 7

From: Sex differences in protein expression in the mouse brain and their perturbations in a model of Down syndrome

Fig. 7

Protein interaction networks. Protein interactions, retrieved from curated public databases, are indicated by lines connecting two nodes. Nodes are color-coded: yellow Hsa21-encoded protein, red human ID protein [18], orange mouse LM protein (The Mammalian Phenotype Database). a Interactions between Hsa21 proteins and sex or thyroid hormone receptors (blue); heavy lines direct interactions with a Dp10 protein. b Interactions of RPPA proteins (green) that showed an abnormal level in at least one brain region/sex/genotype with X chromosome-encoded proteins (blue) that escape silencing by X inactivation [1012]. Arrows indicate activation in the MTOR pathway

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