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Table 7 Correlations of psychophysical reports with activation in common regions located in sensory and affective pain networks (total: N = 24, male: n = 12, female: n = 12)

From: Sex differences in psychophysical and neurophysiological responses to pain in older adults: a cross-sectional study

Region MNI coordinate T statistic Overall associations Temperature Affect (unpleasantness)
  x, y, z   Temp Affect Male Female p valuea Male Female p valuea
Mild pain < warmth   r s r s r s r s   r s r s  
(p value) (p value) (p value) (p value) (p value) (p value)
 (L) dlPFC −4 +32 +34 1.77 −0.05 0.14 0.10 −0.26 0.435 0.11 −0.06 0.719
(0.833) (0.515) (0.771) (0.448) (0.754) (0.868)
 (L) dACC −6 +44 +1 2.59 −0.24 0.05 −0.05 −0.43 0.384 0.11 −0.29 0.384
(0.279) (0.817) (0.890) (0.182) (0.759) (0.386)
 (L) SMA −12 +14 +66 2.77 −0.24 −0.12 0.07 0.13 0.897 0.22 −0.44 0.139
(0.271) (0.603) (0.837) (0.723)   (0.523) (0.172)
 (L) rACC −12 +33 +24 2.62 −0.32 0.01 −0.41 −0.01 0.368 0.34 −0.56 0.037
(0.140) (0.996) (0.249) (0.985) (0.307) (0.080)
Moderate > warmth          
 (R) pINS +51 −35 +17 2.00 0.02 0.26 0.06 −0.20 0.576 0.17 0.20 0.944
(0.936) (0.230) (0.865) (0.549) (0.621) (0.556)
 (R) SI +60 −21 +28 2.28 0.01 0.37 0.01 −0.37 0.395 0.20 0.04 0.726
(0.995) (0.085) (1.000) (0.256) (0.591) (0.916)
 (R) SII +60 −34 +21 1.99 0.07 0.43 0.28 −0.27 0.230 0.51 0.37 0.711
(0.765) (0.043) (0.423) (0.419) (0.140) (0.262)
  1. Values in each cell are beta and (p value). Entries in italics indicate either statistically statistic or meaningful effect sizes and respective differences
  2. MNI Montreal Neurological Institute, L left, R right, dlPFC dorsolateral prefrontal cortex, dACC dorsal anterior cingulate cortex, SMA somatomotor area, rACC rostral anterior cingulate cortex, pINS posterior insula, SI primary somatosensory cortex, SII secondary somatosensory cortex
  3. a z test of independent correlations