Fig. 3

Relaxation induced by bradykinin following pre-constriction with U46619 and following incubation with MgSO₄ (0.2 mmol/l) in vessels isolated from male term pregnancies (empty circle) n = 10, female term pregnancies (empty triangle) n = 10, male preterm pregnancies (filled circle) n = 7 and female preterm pregnancies (filled triangle) n = 7. Data was analysed using a repeated measures three-way ANOVA using treatment × term × sex as the main factors. All observations were made in a minimum of two vessels per placenta, and the average responses were calculated before further statistical analysis. n refers to the number of placenta used. *Denotes P < 0.05 in all cases significant difference between male preterm and all other groups following post hoc analysis. All data are presented as means ± SEM