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Table 1 Revised European-American classification criteria for Sjögren’s syndrome (SS) modified from [15, 17]. Note that not all criteria are required for classification of SS

From: Sex differences in Sjögren’s syndrome: a comprehensive review of immune mechanisms

• Salivary gland inflammation confirmed by histology

• Autoantibodies against Ro/SSA and/or La/SSB

• Ocular signs and symptoms of dry eye

• Oral signs and symptoms of dry mouth including reduced salivary flow (≤1.5 mL in 15 min)