Table 1 Comparison by sex of patient population
From: Sex differences and the role of IL-10 in ischemic stroke recovery
Category | Female | Male | p |
|---|---|---|---|
Age, mean (standard deviation) | 72.934 (14.6709) | 64.471 (14.5089) | 0.000 |
IL-10 levels, median (IQR) in pg/mL | 8.4 (4.163–11.278) | 6.225 (3.81–8.43) | 0.014 |
Stroke risk factor history | |||
Hypertension, % | 80.6 % | 73.3 % | NS |
Heart disease, % | 26.4 % | 30.0 % | NS |
Diabetes, % | 29.2 % | 25.6 % | NS |
Smoking, % | 13.9 % | 20.2 % | NS |
High cholesterol, % | 61.1 % | 65.6 % | NS |
Pre-stroke “good condition” | |||
Baseline modified Barthel ≥ 15, % | 93.4 % | 80 % | NS |
Baseline modified Rankin ≤ 2, % | 87.8 % | 94.9 % | NS |
Markers of stroke severity | |||
Admission NIH, median (IQR) | 6 (3, 16.25) | 4 (2, 14) | NS |
Acute outcomes post-stroke | |||
Discharge NIH, median (IQR) | 3 (0.25, 4.75) | 2.5 (1.00–7.500) | NS |
Change in NIH, median (IQR) | −1.00 (−8.00 to 0.00) | −1.00 (−6.00 to 0.00) | NS |
Death in hospital, % | 14.5 % | 6.3 % | NS |
Death or discharge to hospice, % | 20.0 % | 10.5 % | NS |
Discharge to home, % | 38.2 % | 47.4 % | NS |
3-month negative outcomes | |||
Modified Barthel ≤ 14, % | 25.6 % | 20.4 % | NS |
Modified Rankin score >2, % | 45.0 % | 25.9 % | NS |
Composite negative outcome, % | 40.8 % | 23.5 % | 0.014 |
12-month negative outcomes | |||
Modified Barthel ≤ 14, % | 19.2 % | 16.2 % | NS |
Modified Rankin score >2, % | 32.0 % | 25.0 % | NS |
Composite negative outcome, % | 30.3 % | 18.6 % | NS |