Table 2 Procoagulant, anticoagulant, and cellular adhesion molecules positive microvesicles from apparently healthy women and men separated by age, sex, and menopause status
From: Age- and sex-specific differences in blood-borne microvesicles from apparently healthy humans
Blood-borne microvesicles (MV) | 20–70 years | 20–65 years | 51–70 years | |||
|---|---|---|---|---|---|---|
Women ( N = 82) | Men ( N = 62) | Premenopausal women ( N = 58) | Men ( N = 59) | Postmenopausal women ( N = 24) | Men ( N = 33) | |
Procoagulant positive MV/μL plasma | ||||||
Phosphatidylserine MV | 921* (439, 1,443) | 660 (466, 1,002) | 827* (354, 1,406) | 652 (463, 1,002) | 979 (528, 1,555) | 692 (543, 942) |
Tissue factor MV | 17 (7, 29) | 11 (5, 26) | 16 (8, 29) | 10 (5, 25) | 21 (6, 31) | 17 (4, 27) |
P-selectin MV | 85* (45, 202) | 62 (32, 114) | 90* (31, 202) | 61 (32, 113) | 82 (49, 302) | 61 (18, 111) |
Anticoagulant positive MV/μL plasma | ||||||
Tissue factor pathway inhibitor MV | 7 (4, 20) | 6 (2, 17) | 9 (4, 21) | 7 (2, 18) | 5† (3, 17) | 8 (3, 19) |
Cellular adhesion molecules positive MV/μL plasma | ||||||
ICAM-1 MV | 14 (7, 31) | 14 (7, 29) | 15 (3, 28) | 13 (7, 29) | 20 (9, 39) | 19 (6, 31) |
VCAM-1 MV | 6 (3, 20) | 7 (2, 16) | 7 (3, 21) | 7 (2, 17) | 6 (4, 14) | 8 (4, 21) |