Relative mRNA expression profiles exhibiting sex and age differences of drug transporters. The 30 transporter mRNA expressions for human kidney tissue were graphed to illustrated sex and age differences: (A) males <50 years, (B) males ≥50 years, (C) females <50 years, and (D) females ≥50 years. The bars represent the mean relative mRNA expression; the error bars indicate the standard error mean from n > 3 samples. Statistical analysis was performed using two-way ANOVA (Bonferroni correction); *p < 0.05, **p < 0.05, and #
p < 0.01.