| |
47,XYY
|
Typically developing controls (TDC)
|
48,XXYY
|
47,XXY
|
48,XXXY
|
49,XXXXY
|
47,XXX
|
|---|
| |
N=29
|
N=192
|
N=20
|
N=58
|
N=5
|
N=6
|
N=30
|
|---|
| |
Mean
|
SD
|
Mean
|
SD
|
Mean
|
SD
|
Mean
|
SD
|
Mean
|
SD
|
Mean
|
SD
|
Mean
|
SD
|
|---|
|
Demographic measures
| | | | | | | | | | | | | | |
|
Age
|
12.58
|
4.96
|
12.65
|
5.04
|
14.23
|
5.28
|
12.62
|
4.98
|
10.16
|
7.24
|
13.28
|
4.43
|
12.18
|
5.51
|
|
Gender (M/F)
|
29/0
| |
99/93
| |
20/0
| |
58/0
| |
5/0
| |
6/0
| |
0/30
| |
|
Socioeconomic status (SES)
|
56.75a
|
22.14
|
48.41
|
18.20
|
46.40
|
22.54
|
54.01
|
21.50
|
54.80
|
20.94
|
64.66a
|
18.08
|
41.41
|
17.13
|
|
Handedness (R/L/M)
|
22/4/3
| |
164/12/16
| |
18/1/1
| |
45/6/7
| |
4/0/1
| |
6/0/0
| |
24/2/4
| |
|
Full-scale IQ (FSIQ)
|
90.58a
|
15.41
|
114.50
|
12.56
|
86.52a
|
12.71
|
96.78a
|
16.65
|
77.33a
|
4.72
|
55.50a
|
5.91
|
95.30a
|
14.42
|
|
Verbal IQ (VIQ)
|
87.58a
|
15.12
|
114.14
|
14.23
|
80.31a
|
12.32
|
94.70a
|
16.24
|
73.33a
|
5.85
|
59.25a
|
8.50
|
95.20a
|
14.52
|
|
Performance-IQ (PIQ)
|
95.62a
|
17.01
|
111.88
|
11.59
|
95.94a
|
12.43
|
98.96a
|
16.99
|
86.66a
|
7.02
|
57.25a
|
3.30
|
96.16a
|
15.00
|
|
Testosterone replacement therapy (TRT; currently on/ever on/none)
|
0/0/0
| |
0/0/192
| |
7/7/13
| |
19/23/35
| |
1/2/3
| |
3/4/2
| |
0/0/0
| |
|
MRI measures (cc3)
| | | | | | | | | | | | | | |
|
Intracranial volume (ICV)
|
1.53e +06a
|
1.31e +05
|
1.46e +06
|
1.29e +05
|
1.43e +06
|
1.10e +05
|
1.42e +06
|
1.42e +05
|
1.36e +06
|
4.53e +04
|
1.24e +06a
|
1.03e +05
|
1.29e +06a
|
1.25e +05
|
|
Gray matter volume (GM)
|
8.81e +05a
|
8.69e +04
|
8.43e +05
|
8.67e +04
|
8.17e +05
|
8.24e +04
|
8.14e +05a
|
6.74e +04
|
8.08e +05
|
5.83e +04
|
7.21e +05a
|
7.98e +04
|
7.55e +05a
|
8.77e +04
|
|
White matter volume (WM)
|
5.18e +05a
|
6.27e +04
|
4.89e +05
|
5.91e +04
|
4.91e +05
|
5.82e +04
|
4.75e +05
|
7.52e +04
|
4.46e +05
|
3.51e +04
|
3.99e +05a
|
1.23e +04
|
4.20e +05a
|
4.20e +05a
|
- aSignificant group difference between TDC and diagnostic group.
