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Table 1 Basal hemodynamics, activity, and body weight of adult, aged, and aged-OVX WT and AT 2 R-KO female mice

From: Pressor responsiveness to angiotensin II in female mice is enhanced with age: role of the angiotensin type 2 receptor

  MAP (mmHg) HR (bpm) Activity (units) BW (g)
Adult WT (n = 13) 93 ± 1 570 ± 16 6 ± 1 22 ± 2
Aged WT (n = 11) 94 ± 1 555 ± 13 7 ± 1 28 ± 2
Aged-OVX WT (n = 12) 91 ± 1 548 ± 20 4 ± 1* 31 ± 3
Adult AT2R-KO (n = 12) 94 ± 1 565 ± 12 8 ± 1 23 ± 1
Aged AT2R-KO (n = 14) 93 ± 1 594 ± 11 7 ± 1 27 ± 2
Aged-OVX AT2R-KO (n = 12) 91 ± 1 588 ± 13 5 ± 1 27 ± 3
  1. Data are presented as 24 h mean ± SEM. Data were analyzed using a one-way ANOVA followed by selected post hoc t-tests with Holm-Sidak correction to reduce the risk of type 1 error associated with multiple comparisons. MAP mean arterial pressure, HR heart rate, bpm beats per minute, BW body weight, g grams. *P < 0.05 versus aged WT.