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Table 3 Top networks of sexually dimorphic genes

From: Sexually dimorphic characteristics of the small intestine and colon of prepubescent C57BL/6 mice

ID

Top networks

mol/scorea

SI ♂ vs ♀

  

1

Lipid metabolism, small-molecule biochemistry, vitamin and mineral metabolism

24/41

 

ABCG1♀,ALDH1A3♀,ALS2CR12♂,CD300LD♀,CLN8♂,COX6B2♂,CTRC♀,CYP1B1♂,CYP2C19♀,CYP4B1♀,HCK♀,HDAC11♀,

 
 

mir-181♀,MYBL1♂,MYBL2♀,NCAM2♂,PREX1♀,S100A1♂,SELPLG♀,SH3BP1♀,SLC46A3♂,TIFA♂,TOLLIP♂,UBA3♂

 

2

Lipid metabolism, small-molecule biochemistry, haematological system development and function

18/28

 

ACER3♂,ASAH1♂,BTK♀,CD22♀,LAPTM5♀,NFATC1♀,P2RX7♀,PIK3AP1♀,PIK3CD♀,PLA2G7♀,PLA2G7♀,PLA2G10♀,

 
 

PLCG2♀,PLD2♀,PRR7♀,RASGRP4♀,TNR♂,VPS45♂

 

3

Haematological system development and function, tissue development, cellular movement

17/26

 

AHR♀,CCL11♀,GNPDA1♂,HCLS1♀,IL15♂,KDM5D♂,KDM6A♀,LAMP1♂,MBD1♂,MZB1♀,P2RX1♀,PLCB2♀,PYGL♀,

 

RAC2♀,SRGN♀,TRIM5♂,Uty♂

 

4

Cell-to-cell signalling and interaction, haematological system development and function, immune cell trafficking

17/26

 

BET1♂,BMP7♂,Ceacam1/Ceacam2♂,DLL4♀,EGF♀,ETS1♀,FXYD5♀,HMGCS1♂,mir-148♂,MMP10♀,PARVG♀,

 
 

RUNX3♀,SAMHD1♀,SH3KBP1♀,SH3PXD2B♂,STAP1♀,TRAM2♂

 

Colon ♂ vs ♀

  

1

Cardiovascular system development and function, organismal development, tissue morphology

20/44

 

CABP4♂,DDX3X♀,Dleu2♀,DLK1♂,ITGA2B♂,KLK3♀,MAP3K8♂,mir-10♂,mir-181♂,MTCH2♀,NOS2♂,NPR3♂,

 
 

PDGMC♂,PRKCZ♂,PRX♂,STX6♂,SYT9♂,TNMRSM19♂,TNMRSM11B♂,WT1♂

 

2

Neurological disease, psychological disorders, protein synthesis

16/33

 

BIVm♀,CWC22♀,EIF2S3♂,FUNDC2♀,KDM6A♀,KRT75♂,MED29♂,mir-134♂,PBDC1♀,REEP1♂,RRP12♂,SPTBN2♀,

 
 

STAG3♂,SURF6♀,Uty♂,WDR44♀

 
  1. Networks with p scores ≥25 are presented.
  2. ♂ genes displaying ♂-dominant expression, ♀ genes displaying ♀-dominant expression.
  3. aFocus molecules/score.