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Figure 3 | Biology of Sex Differences

Figure 3

From: Sexually dimorphic characteristics of the small intestine and colon of prepubescent C57BL/6 mice

Figure 3

DNA methylation analysis of the promoter regions of genes displaying sexually dimorphic expression. Significant differential methylation was found in the promoter region of two X-chromosomal genes: (A) Funcd2 and (B) Ddx3x. No differential CpG methylation was found in the promoter region of the autosomal genes (C) Cyp2c66, (D) Alox5ap, (E) Ccr3, (F) Mcpt1, (G) Retnlγ and (H) Nts, all displaying significant sexually dimorphic expression with a FC difference >1.4 between males and females. Blue bars: males; red bars: females. *p < 0.01, **p < 0.001, ***p < 0.0001.

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