Examination of the genetic basis for sexual dimorphism in the Aedes aegypti (dengue vector mosquito) pupal brain

Michael Tomchaney; Keshava Mysore; Longhua Sun; Ping Li; Scott J Emrich; David W Severson; Molly Duman-Scheel

doi:10.1186/s13293-014-0010-x

Table 5 Over-represented GO categories among genes associated with Dsx consensus binding sites

From: Examination of the genetic basis for sexual dimorphism in the Aedes aegypti (dengue vector mosquito) pupal brain

Term	Count	pvalue
GO:0007166—cell surface receptor linked signal transduction	14	0.026157815
GO:0030182—neuron differentiation	12	0.00682396
GO:0007423—sensory organ development	12	0.006946573
GO:0003002—regionalization	11	0.034377574
GO:0007389—pattern specification process	11	0.04735023
GO:0001745—compound eye morphogenesis	10	0.002178058
GO:0048592—eye morphogenesis	10	0.003563147
GO:0048749—compound eye development	10	0.008521908
GO:0001654—eye development	10	0.013504773
GO:0048666—neuron development	10	0.01756628
GO:0007350—blastoderm segmentation	8	0.01232515
GO:0009880—embryonic pattern specification	8	0.016503315
GO:0035282—segmentation	8	0.029278118
GO:0001751—compound eye photoreceptor cell differentiation	7	0.001660725
GO:0001754—eye photoreceptor cell differentiation	7	0.00207928
GO:0046530—photoreceptor cell differentiation	7	0.003406961
GO:0048232—male gamete generation	7	0.008583448
GO:0007283—spermatogenesis	7	0.008583448
GO:0045165—cell fate commitment	7	0.049850932
GO:0022604—regulation of cell morphogenesis	6	0.011632368
GO:0042051—compound eye photoreceptor development	5	0.003084585
GO:0042462—eye photoreceptor cell development	5	0.003302533
GO:0042461—photoreceptor cell development	5	0.005753226
GO:0009968—negative regulation of signal transduction	5	0.029343023
GO:0010648—negative regulation of cell communication	5	0.03026886
GO:0040007—growth	5	0.037232894
GO:0048193—Golgi vesicle transport	4	0.012925753
GO:0016049—cell growth	4	0.017389354
GO:0046552—photoreceptor cell fate commitment	4	0.020430767
GO:0048663—neuron fate commitment	4	0.02374654
GO:0007507—heart development	4	0.044413566
GO:0007479—leg disc proximal/distal pattern formation	3	0.01405488
GO:0035223—leg disc pattern formation	3	0.01405488
GO:0035051—cardiac cell differentiation	3	0.021604074
GO:0035287—head segmentation	3	0.023702413
GO:0007449—proximal/distal pattern formation, imaginal disc	3	0.023702413
GO:0009954—proximal/distal pattern formation	3	0.028137457
GO:0035215—genital disc development	3	0.040521397
GO:0006869—lipid transport	3	0.040521397
GO:0045466—R7 cell differentiation	3	0.045952969
GO:0007419—ventral cord development	3	0.048763797
GO:0048052—R1/R6 cell differentiation	2	0.034007252
GO:0007462—R1/R6 cell fate commitment	2	0.034007252
GO:0031887—lipid particle transport along microtubule	2	0.045086826

A. aegypti genes associated with Dsx consensus sites (defined as genes with Dsx consensus sites located within or 10 kB upstream/dowstream of the genes) grouped under a number of significant GO terms (p < 0.05). The number of genes associated with each GO term (count) and corresponding Fisher's exact test p values are indicated.

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