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Table 1 MicroRNAs showing sex-biased expression in different pathological conditions

From: Influence of sex differences on microRNA gene regulation in disease

Disease/development MicroRNAs Expression changes between males and females Hormone regulated Chromosome linked
Autoimmune diseases     
Systemic lupus erythematosus miR-182 cluster, miR-31, and miR-148a [84] M < F Estrogens -
Neurodegenerative diseases     
Schizophrenia miR-30b [85] M > F Estrogens  
let-7f-2, miR-18b, miR-505, miR-502, miR-188, miR-325, miR-660 and miR-509-3 [41] No expression changes reported (only mutational changes between disease and control)   X chromosome
Cerebral ischemia miR-23a [37] M < F - -
Neurodevelopment miR-322, miR-574, and miR-873 [65] M < F Estrogens -
Metabolic diseases miR-221, let-7 g [86] M < F - -
Breast cancer miR17, let-7a [87]; M < F - -
miR-137 [35] M < F promoter methylation of miR-137 - -
Liver fibrosis miR-29a, miR-29b [88] M < F Estrogens -