| |
Number
|
LV free wall
|
Septum
|
|---|
|
CD, number/mm2
|
MD, number/mm2
|
C/M
|
CD, number/mm2
|
MD, number/mm2
|
C/M
|
|---|
|
Epimyocardium
| | | | | | | |
|
M-Sham
|
7
|
4,929.7 ± 407.7
|
3,142.9 ± 193.6
|
1.59 ± 0.12
|
N/A
|
N/A
|
N/A
|
|
M-MI
|
7
|
3,818.1 ± 169.9*
|
2,178.9 ± 207.6*
|
1.81 ± 0.08*
|
N/A
|
N/A
|
N/A
|
|
F-Sham
|
6
|
5,405.5 ± 418.9
|
4,027.2 ± 262.2§
|
1.35 ± 0.04
|
N/A
|
N/A
|
N/A
|
|
F-MI
|
6
|
5,142.7 ± 773.8
|
3,661.4 ± 312.3††
|
1.39 ± 0.09†
|
N/A
|
N/A
|
N/A
|
|
Endomyocardium
| | | | | | | |
|
M-Sham
|
7
|
6,220.4 ± 329.9
|
3,739.6 ± 195.2
|
1.67 ± 0.05
|
6,107.4 ± 459.6
|
3,783.9 ± 286.5
|
1.62 ± 0.04
|
|
M-MI
|
7
|
4,353.3 ± 687.1*
|
2,704.7 ± 351.0*
|
1.60 ± 0.06
|
5,215.2 ± 592.3
|
3,443.6 ± 262.4
|
1.52 ± 0.09
|
|
F-Sham
|
6
|
5,477.4 ± 396.5
|
4,032.1 ± 305.2
|
1.36 ± 0.05§
|
5,361.5 ± 908.9
|
3,938.7 ± 346.8
|
1.34 ± 0.12§
|
|
F-MI
|
6
|
4,492.8 ± 648.0
|
2,709.2 ± 337.3*
|
1.66 ± 0.13*
|
5,510.2 ± 717.4
|
3,875.4 ± 359.8
|
1.37 ± 0.11
|
- Values are the mean ± SEM. n, number of rats; CD, capillary density; MD, myocyte density; C/M, capillary-to-myocyte ratio; N/A, mot applicable. Note that in septum all parameters were analyzed only in LV endomyocardium. A two-way ANOVA revealed a statistically significant interaction between the effects of sex and the experimental model on the capillary-to-cardiac myocyte ratio in free wall endomyocardium, F (1, 22) = 6.307, P = 0.025. *P < 0.05 vs. corresponding Sham group; §P < 0.05 vs. M-Sham; †P < 0.05 and ††P < 0.01 vs. M-MI.
