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Table 2 Statistical values associated with serotonin- and dopamine-related gene expression in the frontal cortex

From: Sex chromosome complement regulates expression of mood-related genes

  Gene Sex chromosome Gonadal sex Activational Significant interactions
Serotonin and dopamine receptors Htr1a F= 4.77; df= 1; F= 3.65; df= 1; F= 20.58; df= 1; Gonadal × Activational:
p< 0.04 p< 0.10 p< 0.001 F = 11.92; df = 3; p < 0.001
Htr2a F = 0.22; df = 1; F= 4.32; df= 1; F = 0.11; df = 1;  
p > 0.60 p= 0.040 p > 0.70
Htr2c F= 6.29; df= 1; F = 2.16; df = 1; F = 1.88; df = 1;  
p< 0.02 p > 0.10 p > 0.15
Drd1a F= 4.01; df= 1; F = 0.049; df = 1; F = 0.13; df = 1; Gonadal × Activational:
p< 0.05 p > 0.80 p > 0.70 F = 2.86; df = 3; p < 0.045
cAMP/PKA pathway Adcy1 F = 1.28; df = 1; F= 4.59; df= 1; F = 0.55; df = 1; Sex chromosome × Activational:
p > 0.25 p< 0.04 p > 0.45 F = 2.70; df = 3; p < 0.05
    Sex chromosome × Gonadal × Activational: F = 2.94; df = 7; p < 0.01
Adcy2 F= 3.32; df= 1; F = 2.35; df = 1; F= 8.83; df= 1;  
p= 0.071 p > 0.10 p< 0.005
Adcy5 F= 5.73; df= 1; F = 2.94; df = 1; F = 0.062; df = 1; Genetic × Activational:
p< 0.02 p = 0.089 p > 0.75 F = 2.68; df = 3; p = 0.11
    Gonadal × Activational:
F = 3.63; df = 3; p < 0.02
Adcy7 F= 5.37; df= 1; F = 0.94; df = 1; F = 0.08; df = 1;  
p< 0.025 p > 0.30 p > 0.75
Cdk5 F= 2.93; df= 1; F = 1.01; df = 1; F= 2.90; df= 1; Gonadal × Activational:
p= 0.09 p > 0.30 p= 0.091 F = 2.67; df = 3; p = 0.051
AKT pathway Akt1 F= 3.75; df= 1; F = 0.61; df = 1; F= 5.99; df= 1; Sex chromosome × Gonadal:
p= 0.056 p > 0.40 p< 0.02 F =2.53; df = 3; p = 0.11
    Sex chromosome × Activational:
F = 4.82; df = 3; p < 0.005
    Gonadal × Activational:
F = 4.16; df = 7; p < 0.01
Akt2 F = 0.89; df = 1; F= 4.64; df= 1; F = 2.10; df = 1;  
p > 0.30 p< 0.035 p > 0.10
Akt3 F= 3.57; df= 1; F= 7.16; df= 1; F= 4.72; df= 1; Sex chromosome × Activational:
p= 0.062 p< 0.01 p< 0.035 F = 2.64; df = 3; p = 0.11
    Gonadal × Activational:
F = 6.53; df = 3; p < 0.001
Other serotonin- and dopamine-related genes App F= 6.56; df= 1; F = 1.43; df = 1; F = 0.22; df = 1; Gonadal × Activational:
p< 0.015 p > 0.20 p > 0.60 F = 2.17; df = 3; p = 0.096
    Sex chromosome × Gonadal ×
Activational: F = 2.62; df = 7; p = 0.11
Pdyn F = 0.29; df = 1; F = 0.38; df = 1; F = 2.09; df = 1;  
  p > 0.55 p > 0.50 p > 0.15  
  1. Numbers in bold indicate comparisons that were significant at 5% false discovery rate with correction for the 14 genes examined. cAMP cyclic adenosine monophosphate, PKA protein kinase A.