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Figure 2 | Biology of Sex Differences

Figure 2

From: Sex chromosome complement regulates expression of mood-related genes

Figure 2

Effects of sex-related factors on expression of serotonin (5HT)- and dopamine (DA)-related genes. (A) 5HT- and DA-related genes exhibiting significant main effects of sex chromosome complement (Htr1a, Htr2c, Drd1a, Adcy1, Adcy2, Adcy5, Adcy7, Akt1, Akt3, App), gonadal sex (Htr1a, Htr2a, Adcy1, Adcy5, Akt2, Akt3), and/or circulating testosterone (Htr1a, Adcy2, Akt1, Akt3). (B) 5HT- and DA-related genes with significant interactions of gonadal sex and circulating testosterone (Htr1a, Drd1a, Adcy5, Akt1, Akt3), sex chromosome complement and circulating testosterone (Adcy1, Akt1), or interaction of all three sex-related factors (Adcy1). Numbers at the base of bars indicate N. ***p < 0.001, **p < 0.01, *p < 0.05, #p < 0.1; T testosterone, B blank, F gonadal female, M gonadal male.

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