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Table 2 Renal evaluation of 32-wk-old intact, placebo-, and estrogen-treated orchidectomized NZB/W F1 mice

From: Sex differences in the expression of lupus-associated miRNAs in splenocytes from lupus-prone NZB/WF1 mice

  Intact 32 wks Placebo 32 wks Estrogen 32 wks
Mouse ID #1 #2 #3 #4 #5 #1 #2 #3 #4 #5 #1 #2
Glomerular scorea 1 2 0 0 0 1 1 0 0 2 0 2
Tubular scorea 1 1 1 1 2 1 1 1 1 0 1 1
Interstitial scorea 0 0 0 0 0 2 0 0 0 0 0 1
Vessel scorea 1 0 0 0 0 1 1 0 0 2 0 1
Overall renal score 3 3 1 1 2 5 3 1 1 4 1 5
Proteinuriab +/- +/- - + +/- +/- ++ +/- +/- + - ++/-
  1. a0 = perfect, no change; 1 = minimal; 2 = moderate; 3 = marked; and 4 = severe; bnegative or trace, -; 30, +; 30–100, +/-; 100, ++; 100–500, ++/-, 500, +++.