Table 2 Renal evaluation of 32-wk-old intact, placebo-, and estrogen-treated orchidectomized NZB/W F1 mice
| Â | Intact 32 wks | Placebo 32 wks | Estrogen 32 wks | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mouse ID | #1 | #2 | #3 | #4 | #5 | #1 | #2 | #3 | #4 | #5 | #1 | #2 |
Glomerular scorea | 1 | 2 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 2 | 0 | 2 |
Tubular scorea | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 0 | 1 | 1 |
Interstitial scorea | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 1 |
Vessel scorea | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 2 | 0 | 1 |
Overall renal score | 3 | 3 | 1 | 1 | 2 | 5 | 3 | 1 | 1 | 4 | 1 | 5 |
Proteinuriab | +/- | +/- | - | + | +/- | +/- | ++ | +/- | +/- | + | - | ++/- |