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Table 1 Renal pathological changes in male and female NZB/W F1 mice

From: Sex differences in the expression of lupus-associated miRNAs in splenocytes from lupus-prone NZB/WF1 mice

  Male 23 wks   Female 23 wks Male 30 wks Female 30 wks
Mouse ID #1 #2 #3 #4 #5 #1 #2 #3 #4 #5 #1 #2 #3 #4 #1 #2 #3 #4
Glomerular scorea 0 0 0 1 1 0 1 0 0 0 0 0 0 0 1 0 2 3
Tubular scorea 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 2 3
Interstitial scorea 0 1 0 0 0 0 0 0 1 0 0 0 0 0 0 0 2 3
Vessel scorea 0 0 0 0 0 0 0 0 0 0 0 1 1 1 1 0 1 2
Overall renal score 0 1 0 1 1 0 1 0 1 0 0 1 1 1 2 0 7 11
Proteinuriab +/- +/- + - - + +/- - - + + - - ++ ++ + +++ +++
  1. a0 = perfect, no change; 1 = minimal; 2 = moderate; 3 = marked; and 4 = severe; bnegative or trace, -; 30, +; 30–100, +/-; 100, ++; 100–500, ++/-, 500, +++.
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