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Figure 4 | Biology of Sex Differences

Figure 4

From: Anti-Müllerian hormone may regulate the number of calbindin-positive neurons in the sexually dimorphic nucleus of the preoptic area of male mice

Figure 4

The size of neuronal soma in the CALB-SDN is dimorphic after puberty. The bars are the mean size of the cell body of the calbindin+ve neurons ± the standard error of the mean of six mice. The Amh genotype (+/+ or -/-) is shown beneath each bar. (A) Twenty-day-old mice. There is no effect of sex or genotype at this age. (B) Adult mice. *1: There was a significant effect of sex (p < 0.001, two-way ANOVA) but not of genotype. *2: The Amh+/+ males were significantly different to both of the female groups (p = 0.005 Amh+/+ and p = 0.004 Amh-/-, Student’s t test). *3: The adult Amh-/- males were also significantly different to both of the adult female groups (p = 0.011 Amh+/+, p = 0.008 Amh-/-, Student’s t test). (C) The bars illustrate the mean change in cell size after 20 days. In the female mice, the change in size was marginally significant (p = 0.048, two-way ANOVA of age and genotype). ♂, male; ♀, female.

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