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Table 2 Biological and clinical features associated to sexual dimorphism in inflammation

From: Sex and inflammation in respiratory diseases: a clinical viewpoint

 

Inflammatory mediators

Female

Male

Biological markers

CRP

⬆

⬇

ESR

⬆

⬇

IL-8

⬆

⬇

IL-1β, IL-6, TNF-α

⬇

⬆

CD99

⬇

⬆

Hematological markers

Neutrophil count

⬆

⬇

Monocyte count

⬇

⬆

Clinical features

Outcome in acute inflammatory processes (septic shock, burns, trauma)

Better prognosis

Worse prognosis

 

Outcome in chronic inflammatory processes (severe asthma, cystic fibrosis, BPCO)

Worse prognosis

Better prognosis

  1. The table summarizes the main trends observe in the literature. Up arrow denotes increase; down arrow, decrease.