Skip to main content

Advertisement

Table 1 Effect of treatment on body weight, kidney weight, heart weight, and albuminuria of rats

From: Growth hormone exacerbates diabetic renal damage in male but not female rats

  Initial BW (g) Final BW (g) KW (g) HW (g) Albuminuria (mg/day)
Female
  Control 244.5 ± 5.5 284.0 ± 9.0 1.52 ± 0.04 0.99 ± 0.11 2.9 ± 1.2
  STZ 225.3 ± 1.8 201.0 ± 4.4* 2.20 ± 0.02* 0.94 ± 0.04 11.3 ± 2.7*
  STZ + GH 227.4 ± 2.3 227.4 ± 18.7 2.36 ± 0.11* 0.95 ± 0.07 8.6 ± 1.8*
Male
  Control 369.7 ± 2.7 461.0 ± 14.0 2.68 ± 0.10 1.42 ± 0.02 3.1 ± 0.4
  STZ 352.8 ± 8.1 251.8 ± 22.0** 2.75 ± 0.21 1.00 ± 0.08** 10.4 ± 0.8**
  STZ + GH 353.0 ± 8.7 249.0 ± 25.6** 2.85 ± 0.19 1.13 ± 0.10** 16.1 ± 1.7**,***
  1. BW, Body weight; KW, Kidney weight; HW, Heart weight. * P > 0.05 vs sham female; ** P > 0.05 vs sham male; *** P > 0.05 vs STZ male by one-way ANOVA and Tukey’s post hoc tests. (n = 8 for each group).