From: Growth hormone exacerbates diabetic renal damage in male but not female rats
Initial BW (g) | Final BW (g) | KW (g) | HW (g) | Albuminuria (mg/day) | |
---|---|---|---|---|---|
Female | |||||
Control | 244.5 ± 5.5 | 284.0 ± 9.0 | 1.52 ± 0.04 | 0.99 ± 0.11 | 2.9 ± 1.2 |
STZ | 225.3 ± 1.8 | 201.0 ± 4.4* | 2.20 ± 0.02* | 0.94 ± 0.04 | 11.3 ± 2.7* |
STZ + GH | 227.4 ± 2.3 | 227.4 ± 18.7 | 2.36 ± 0.11* | 0.95 ± 0.07 | 8.6 ± 1.8* |
Male | |||||
Control | 369.7 ± 2.7 | 461.0 ± 14.0 | 2.68 ± 0.10 | 1.42 ± 0.02 | 3.1 ± 0.4 |
STZ | 352.8 ± 8.1 | 251.8 ± 22.0** | 2.75 ± 0.21 | 1.00 ± 0.08** | 10.4 ± 0.8** |
STZ + GH | 353.0 ± 8.7 | 249.0 ± 25.6** | 2.85 ± 0.19 | 1.13 ± 0.10** | 16.1 ± 1.7**,*** |