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Table 1 Effect of treatment on body weight, kidney weight, heart weight, and albuminuria of rats

From: Growth hormone exacerbates diabetic renal damage in male but not female rats

 

Initial BW (g)

Final BW (g)

KW (g)

HW (g)

Albuminuria (mg/day)

Female

  Control

244.5 ± 5.5

284.0 ± 9.0

1.52 ± 0.04

0.99 ± 0.11

2.9 ± 1.2

  STZ

225.3 ± 1.8

201.0 ± 4.4*

2.20 ± 0.02*

0.94 ± 0.04

11.3 ± 2.7*

  STZ + GH

227.4 ± 2.3

227.4 ± 18.7

2.36 ± 0.11*

0.95 ± 0.07

8.6 ± 1.8*

Male

  Control

369.7 ± 2.7

461.0 ± 14.0

2.68 ± 0.10

1.42 ± 0.02

3.1 ± 0.4

  STZ

352.8 ± 8.1

251.8 ± 22.0**

2.75 ± 0.21

1.00 ± 0.08**

10.4 ± 0.8**

  STZ + GH

353.0 ± 8.7

249.0 ± 25.6**

2.85 ± 0.19

1.13 ± 0.10**

16.1 ± 1.7**,***

  1. BW, Body weight; KW, Kidney weight; HW, Heart weight. * P > 0.05 vs sham female; ** P > 0.05 vs sham male; *** P > 0.05 vs STZ male by one-way ANOVA and Tukey’s post hoc tests. (n = 8 for each group).