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Figure 4 | Biology of Sex Differences

Figure 4

From: Growth hormone exacerbates diabetic renal damage in male but not female rats

Figure 4

Effects of STZ and GH treatment on renal CD68 immunoreactivity. (A) No significant changes were observed in CD68 protein expression in kidneys from diabetic female rats. While CD68 staining was not increased in kidneys from STZ-only-treated rats, GH significantly increased CD68 staining in the glomeruli and tubules in diabetic male, but not female, rats. * P < 0.01 compared to all other data (B) Representative images of CD68+ cells in kidney sections (dark brown dots). The intensity of staining is significantly increased in the STZ + GH-treated males. Original magnification is × 400, and bar represents 100 μm.

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