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Figure 3 | Biology of Sex Differences

Figure 3

From: Growth hormone exacerbates diabetic renal damage in male but not female rats

Figure 3

Effects of STZ and GH treatment on renal MCP immunoreactivity. (A) STZ increases the MCP-1 staining in kidneys from diabetic male and female rats; however, GH treatment increased MCP-1 only in kidneys from diabetic male rats. * P < 0.01 vs control and # P < 0.05 vs female. (B) Representative images show an increase in brown staining on dilated and injured tubules (solid arrows show dilated tubules, and dashed arrows show brown staining). Original magnification is × 400, and bar represents 100 μm.

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