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Figure 2 | Biology of Sex Differences

Figure 2

From: Sex differences matter in the gut: effect on mucosal immune activation and inflammation

Figure 2

Pathways associated immune activation are upregulated in the gut mucosa in women. (A) A large cluster of the increased levels of gene transcription in the mucosal microenvironment includes genes and pathways associated with immune activation, antigen presentation and inflammation (M: male, F:female). Specific pathways that were upregulated in the microenvironment of the female gut mucosal tissue over baseline of male mucosal tissue include (B) IL1 Signaling, (C) IL2 Signaling and (D) Antigen presentation (Red: Increase in expression, Green: decrease in expression).

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