Figure 1
From: Sex differences matter in the gut: effect on mucosal immune activation and inflammation
The microenvironment of the gut in women has a transcriptional profile indicative of increased activation and turnover. Transcriptional analysis of jejunal mucosa was performed using oligonucleotide microarray analysis. (A) All samples cluster in accordance with the gender of the participant. A large portion of the gene expression included genes that were upregulated in women as compared to men (B) The genes that were upregulated clustered into functional categories of IGF-1 signaling, Integrin Signaling and other signaling pathways (p<.05).