Table 3 Genes showing developmental changes are enriched for genes altered by hypophysectomy

# of overlapping genes

Fold enrichment

Fisher Test p -value

# of overlapping genes

Fold enrichment

Fisher Test p -value

All genes up regulated in male liver 3-8 wk (1,542 genes)

213

1.39

3.05E-06

306

2.04

2.13E-30

All genes down regulated in male liver 3-8 wk (1,773 genes)

393

2.23

7.12E-47

163

0.95

0.479

B. Background: All genes (22,635)

Genes up regulated in female hypophysectomized liver (1,521 genes)

Genes down regulated in female hypophysectomized liver (1,535 genes)

# of overlapping genes

Fold enrichment

Fisher Test p-value

# of overlapping genes

Fold enrichment

Fisher Test p-value

All genes up regulated in female liver 3-8 wk (1,070 genes)

131

1.82

2.38E-10

151

2.08

2.91E-16

All genes down regulated in female liver 3-8 wk (1,364 genes)

203

2.21

5.87E-24

139

1.50

5.16E-06