Skip to main content

Advertisement

Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Table 1 Gene count distribution and onset of sex specificity

From: Sex-specific mouse liver gene expression: genome-wide analysis of developmental changes from pre-pubertal period to young adulthood

Sex specificity (defined at 8 wk) Onset at 3 wk Onset at 4 wk Onset at 8 wk No sex specificity Total genes
   Number of genes   
Male-specific 7 54 526* 0 587
Female-specific 9 104 512** 0 625
Sex-independent 23 (M), 56 (F)*** 59 (M), 86 (F)*** 0 4279 4503
  1. The onset of sex-specificity for 1,037 out of 1,212 adult sex-specific genes occurred after 4 wk and by 8 wk. 224 of the 4,503 adult sex-independent genes met the thresholds for sex-differential expression at 3 or 4 wk, but not at 8 wk, however, only 13 of these genes showed the same sex-bias at 3 wk as at 4 wk. Three of the 7 male-specific genes showing sex specificity at 3 wk are Y-chromosome genes
  2. * Includes 5 genes found to be male-specific at 8 wk, but female-specific at 3 or 4 wk
  3. ** Includes 6 genes found to female-specific at 8 wk, but male-specific at 3 or 4 wk
  4. *** These genes exhibit either male-specificity (M) or female-specificity (F) at 3 or 4 wk, as noted, but show sex-independent expression at 8 wk