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Figure 12 | Biology of Sex Differences

Figure 12

From: Sex differences in primary hypertension

Figure 12

Generation of the four core genotype. The Sry gene was spontaneously deleted from the Y chromosome (Y-) and transferred to an autosome resulting in the XY- Sry male mouse. Breeding XX females with XY- Sry males produces the four core genotype: XY- and XX females and XY- Sry and XXSry males. We refer to XX and XY- as XX and XY-Females and XXSry and XY- Sry as XX- and XY-Males throughout the text.

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