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Table 4 Plasma lipid peroxidation, thiols and taurine

From: Oral contraceptives modify DNA methylation and monocyte-derived macrophage function

Type

Fs, n = 72

FOCs, n = 67

P value

FOCA+, n = 28

FOCA-, n = 39

P value

Malonyldialdehyde (μM)

4.2 ± 1.9, n = 69

4.1 ± 1.7, n = 66

NS

3.7 (1.3 to 8.6), n = 27

3.9 (0.9 to 8.6), n = 39

NS

Homocysteine (μM)

8.7 (4.0 to 41.1)

8.3 (4.3 to 16.7)

NS

8.3 ± 2.9

8.9 ± 2.9

NS

Cysteine (μM)

195.6 (118.9 to 350.7)

176.6 (115.8 to 318.4)

0.003

181.5 ± 39.8

186.6 ± 45.4

NS

Cysteinglycine (μM)

18.7 (7.6 to 33.6)

19.5 (7.4 to 38.8)

NS

20.6 (11.4 to 38.8)

18.9 (7.4 to 33.0)

NS

Glucylcysteine (μM)

4.5 ± 1.0

4.5 ± 0.9

NS

4.4 ± 1.0

4.5 ± 0.9

NS

Glutathione (μM)

7.4 (2.7 to 14.8)

8.0 (3.9 to 14.9)

NS

8.0 ± 2.4

8.2 ± 2.0

NS

Taurine (μM)

64.1 (31.7 to 202.7)

59.6 (27.3 to 158.9)

NS

60.9 (27.3 to 146.8)

59.4 (36.3 to 158.9)

NS

  1. Data are expressed as the mean ± SD or as medians and ranges; n indicates the number of samples used to calculate the statistics.
  2. FOCA+/FOCA- = FOCs further stratified as a function of androgenic (FOCA+) and non-androgenic (FOCA-) properties of progestins; FOCs = women treated with OCs for at least 3 months; Fs = women who had not used OCs for at least 3 months to ensure a sufficient washout period; NS = not significant; OC = oral contraceptive.