Table 1 Main characteristics of each subgroup of females
From: Oral contraceptives modify DNA methylation and monocyte-derived macrophage function
Characteristic | Fs (n = 85) | FOCs (n = 77) | P value | FOCA+ (n = 33) | FOCA to (n = 44) | P value |
|---|---|---|---|---|---|---|
Age (years) | 27.0 (18.0 to 40.0) | 27.0 (20.0 to 39.0) | NS | 28.0 (20.0 to 39.0) | 26.0 (20.0 to 39.0) | NS |
Weight (kg) | 53.0 (38.0 to 78.0) | 54.0 (43.0 to 75.0) | NS | 54.0 (45.0 to 70.0) | 55.0 (43.0 to 75.0) | NS |
Body mass index (kg/cm2) | 20.2 (17.0 to 28.0) | 21.0 (17.0 to 28.0) | NS | 21.5 ± 2.1 | 21.1 ± 2.4 | NS |
Hemoglobin (g/dl) | 12.7 ± 1.1 | 12.6 ± 1.0 | NS | 12.4 ± 1.0 | 12.8 ± 0.9 | 0.044 |
Saturation (%) | 24.8 ± 11.5, n = 63 | 22.8 ± 10.2, n = 62 | NS | 25.1 (3.7 to 44.5) | 16.0 (5.5 to 51.9) | 0.005 |
White blood cells (109 cells/l) | 6.5 (3.62 to 11.7) | 6.8 (4.1 to 12.9) | NS | 6.4 ± 1.6 | 7.1 ± 1.4 | 0.031 |
High-density lipoprotein (mg/dl) | 60.9 ± 11.2 | 69.3 ± 13.5 | < 0.001 | 65.0 ± 11.6 | 72.6 ± 14.1 | 0.014 |
Low-density lipoprotein (mg/dl) | 108.5 (68.0 to 166.0) | 111.0 (35.0 to 229.0) | NS | 114.5 (70.0 to 229.0) | 108.5 (35.0 to 193.0) | NS |
High-density/low-density lipoprotein | 0.6 (0.3 to 1.3) | 0.6 (0.2 to 2.0) | NS | 0.6 (0.2 to 0.9) | 0.6 (0.3 to 2.0) | NS |
Triglycerides (mg/dl) | 68.0 (33.0 to 205.0) | 90.5 (42.0 to 236.0) | < 0.001 | 83.0 (42.0 to 174.0) | 99.5 (48.0 to 236.0) | NS |
Glycaemia (mg/dl) | 76.0 (30.0 to 110.0) | 77.0 (50.0 to 93.0) | NS | 73.7 ± 9.4 | 77.6 ± 8.3 | NS |
Creatinine (mg/dl) | 0.7 (0.6 to 0.9) | 0.7 (0.6 to 1.0) | NS | 0.7 (0.6 to 1.0) | 0.71 (0.62 to 0.87) | NS |
Creatinine clearance (ml/min) | 101.9 ± 16.3 | 102.3 ± 14.6 | NS | 99.92 ± 14.23 | 104.08 ± 14.88 | NS |
Uric acid (mg/dl) | 3.6 ± 0.9 | 3.4 ± 0.8 | NS | 3.3 ± 0.9 | 3.4 ± 0.8 | NS |
Urea (mg/dl) | 27.5 (14.8 to 55.1) | 28.4 (18.4 to 47.2) | NS | 29.7 ± 7.8 | 28.8 ± 6.1 | NS |
Total bilirubin (mg/dl) | 0.5 (0.2 to 2.1) | 0.4 (0.10 to 1.9) | < 0.001 | 0.5 (0.1 to 0.9) | 0.4 (0.2 to 1.93) | NS |
Alkaline phosphatase (U/l) | 59.0 (38.0 to 115.0) | 55.0 (34.0 to 99.0) | 0.029 | 53.4 ± 10.1 | 56.9 ± 14.6 | NS |
Aspartate aminotransferase (U/l) | 19.0 (12.0 to 39.0) | 18.0 (10.0 to 60.0) | NS | 18.0 (11.0 to 29.0) | 18.0 (10.0 to 60.0) | NS |
Alanine aminotransferase (U/l) | 17.0 (6.0 to 64.0) | 15.0 (6.0 to 38.0) | NS | 15.0 (6.0 to 38.0) | 15.0 (7.0 to 31.0) | NS |
γ-Glutamyl transpeptidase (U/l) | 15.0 (7.0 to 98.0) | 14.0 (7.0 to 34.0) | 0.018 | 15.0 (7.0 to 30.0) | 12.0 (7.0 to 34.0) | 0.024 |
Calcium (mg/dl) | 9.4 (8.3 to 10.4) (80) | 9.4 (8.4 to 10.1) | NS | 9.2 ± 0.4 | 9.5 ± 0.4 | 0.003 |
Sodium (mEq/l) | 140.0 (134.0 to 146.0) | 140.0 (135.0 to 147.0) | NS | 140.0 (135.0 to 147.0) | 140.0 (136.0 to 144.0) | NS |
Potassium (mEq/l) | 4.1 (3.5 to 4.8) | 4.10 (3.5 to 6.9) | NS | 4.10 (3.6 to 6.9) | 4.1 (3.5 to 4.8) | NS |
Prothrombin time (s) | 10.7 (9.8 to 11.3), n = 71 | 10.4 (9.6 to 11.6), n = 68 | < 0.001 | 10.6 ± 0.3, n = 28 | 10.4 ± 0.4, n = 40 | NS |