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Table 1 Main characteristics of each subgroup of females

From: Oral contraceptives modify DNA methylation and monocyte-derived macrophage function

Characteristic Fs (n = 85) FOCs (n = 77) P value FOCA+ (n = 33) FOCA to (n = 44) P value
Age (years) 27.0 (18.0 to 40.0) 27.0 (20.0 to 39.0) NS 28.0 (20.0 to 39.0) 26.0 (20.0 to 39.0) NS
Weight (kg) 53.0 (38.0 to 78.0) 54.0 (43.0 to 75.0) NS 54.0 (45.0 to 70.0) 55.0 (43.0 to 75.0) NS
Body mass index (kg/cm2) 20.2 (17.0 to 28.0) 21.0 (17.0 to 28.0) NS 21.5 ± 2.1 21.1 ± 2.4 NS
Hemoglobin (g/dl) 12.7 ± 1.1 12.6 ± 1.0 NS 12.4 ± 1.0 12.8 ± 0.9 0.044
Saturation (%) 24.8 ± 11.5, n = 63 22.8 ± 10.2, n = 62 NS 25.1 (3.7 to 44.5) 16.0 (5.5 to 51.9) 0.005
White blood cells (109 cells/l) 6.5 (3.62 to 11.7) 6.8 (4.1 to 12.9) NS 6.4 ± 1.6 7.1 ± 1.4 0.031
High-density lipoprotein (mg/dl) 60.9 ± 11.2 69.3 ± 13.5 < 0.001 65.0 ± 11.6 72.6 ± 14.1 0.014
Low-density lipoprotein (mg/dl) 108.5 (68.0 to 166.0) 111.0 (35.0 to 229.0) NS 114.5 (70.0 to 229.0) 108.5 (35.0 to 193.0) NS
High-density/low-density lipoprotein 0.6 (0.3 to 1.3) 0.6 (0.2 to 2.0) NS 0.6 (0.2 to 0.9) 0.6 (0.3 to 2.0) NS
Triglycerides (mg/dl) 68.0 (33.0 to 205.0) 90.5 (42.0 to 236.0) < 0.001 83.0 (42.0 to 174.0) 99.5 (48.0 to 236.0) NS
Glycaemia (mg/dl) 76.0 (30.0 to 110.0) 77.0 (50.0 to 93.0) NS 73.7 ± 9.4 77.6 ± 8.3 NS
Creatinine (mg/dl) 0.7 (0.6 to 0.9) 0.7 (0.6 to 1.0) NS 0.7 (0.6 to 1.0) 0.71 (0.62 to 0.87) NS
Creatinine clearance (ml/min) 101.9 ± 16.3 102.3 ± 14.6 NS 99.92 ± 14.23 104.08 ± 14.88 NS
Uric acid (mg/dl) 3.6 ± 0.9 3.4 ± 0.8 NS 3.3 ± 0.9 3.4 ± 0.8 NS
Urea (mg/dl) 27.5 (14.8 to 55.1) 28.4 (18.4 to 47.2) NS 29.7 ± 7.8 28.8 ± 6.1 NS
Total bilirubin (mg/dl) 0.5 (0.2 to 2.1) 0.4 (0.10 to 1.9) < 0.001 0.5 (0.1 to 0.9) 0.4 (0.2 to 1.93) NS
Alkaline phosphatase (U/l) 59.0 (38.0 to 115.0) 55.0 (34.0 to 99.0) 0.029 53.4 ± 10.1 56.9 ± 14.6 NS
Aspartate aminotransferase (U/l) 19.0 (12.0 to 39.0) 18.0 (10.0 to 60.0) NS 18.0 (11.0 to 29.0) 18.0 (10.0 to 60.0) NS
Alanine aminotransferase (U/l) 17.0 (6.0 to 64.0) 15.0 (6.0 to 38.0) NS 15.0 (6.0 to 38.0) 15.0 (7.0 to 31.0) NS
γ-Glutamyl transpeptidase (U/l) 15.0 (7.0 to 98.0) 14.0 (7.0 to 34.0) 0.018 15.0 (7.0 to 30.0) 12.0 (7.0 to 34.0) 0.024
Calcium (mg/dl) 9.4 (8.3 to 10.4) (80) 9.4 (8.4 to 10.1) NS 9.2 ± 0.4 9.5 ± 0.4 0.003
Sodium (mEq/l) 140.0 (134.0 to 146.0) 140.0 (135.0 to 147.0) NS 140.0 (135.0 to 147.0) 140.0 (136.0 to 144.0) NS
Potassium (mEq/l) 4.1 (3.5 to 4.8) 4.10 (3.5 to 6.9) NS 4.10 (3.6 to 6.9) 4.1 (3.5 to 4.8) NS
Prothrombin time (s) 10.7 (9.8 to 11.3), n = 71 10.4 (9.6 to 11.6), n = 68 < 0.001 10.6 ± 0.3, n = 28 10.4 ± 0.4, n = 40 NS
  1. Data are expressed as the mean ± SD or as medians and ranges; n indicates the number of subjects used to calculate the statistics, and these may vary due to the unavailability of enough plasma to complete the analyses.
  2. NS = not significant.