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Table 5 Psychosocial variables in knee OA

From: Neural and psychosocial contributions to sex differences in knee osteoarthritic pain

Study

Findings

Dekker et al., 2009 [17]

People with OA have a higher prevalence of depression and anxiety and this is associated with worse pain and greater healthcare utilization; sex differences not reported.

Fransen et al., 2002 [71]

Systematic review showing exercise reduces pain and improves function in OA; sex differences not reported.

Lamb et al., 2008 [16]

Behavioral interventions prior to surgery improve self-efficacy, decrease pain, and improve function in OA; sex differences not reported.

Lorig et al., 2008 [19]

Self-management strategies improve self-efficacy and pain catastrophizing in OA; sex differences not reported.

Marks et al., 2009 [18]

People with depression have reduced function and recover slower after total joint replacement; sex differences not reported.

Pells et al., 2008 [69]

Higher self-efficacy scores in pain and function correlate with lower pain and greater function in OA; sex differences not reported.

Perrot et al., 2008 [66]

Passive coping strategies generally result in higher pain and lower function; sex differences not reported.

Riddle et al., 2010 [68]

Higher catastrophizing scores are associated with poor outcome 6 months after total knee replacement; sex differences not reported.

Shelby et al., 2008 [70]

Self-efficacy beliefs underlie the relation between pain catastrophizing and pain; sex differences not reported.

Singh et al., 2008 [2]

Pessimistic patients have more moderate-to-severe pain 2 years after total knee replacement; sex differences not reported.

Somers et al., 2009 [72]

Pain-related fear explains part of the variance in physical disability, pain, and function in OA; sex differences not reported.

Sullivan et al., 2009 [14]

Higher pain catastrophizing scores are associated with greater pain and disability 6 weeks after total joint replacement; sex differences not reported.

Tonelli et al., 2011 [15]

Shows greater pain during movement in women with late stage OA; no difference in depression, anxiety or pain catastrophizing between sexes in OA; models predictors of movement pain in women and men with OA.

Tsai, 2007 [73]

Depression tendency in OA explain a portion of the sex differences in pain.

Unruh, 1996 [67]

Review discussing sex differences in the clinical pain experience.

  1. All studies were performed in human subjects and included both men and women.