Figure 3From: Neural and psychosocial contributions to sex differences in knee osteoarthritic pain Example of temporal summation in response to pressure applied either to the knee joint or to the anterior tibialis muscle at the pressure-pain threshold in people with osteoarthritis. VAS scores were normalized for comparison by subtracting the first stimulus pain score from subsequent pain scores. Group A had more clinical pain with VAS scores of 6/10 or greater and Group B had clinical pain scored less than 6/10. These two groups were compared to age and sex-matched controls. The greatest temporal summation occurred in the group with the highest pain scores. *, p<0.05 Group A different from controls and Group B; Group B different from Controls. Reprinted from [5] with permission of the International Association for the Study of Pain.Back to article page