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Figure 3 | Biology of Sex Differences

Figure 3

From: Sex-specific signaling through Toll-Like Receptors 2 and 4 contributes to survival outcome of Coxsackievirus B3 infection in C57Bl/6 mice

Figure 3

Male mice show an increase in the number TLR4 expressing CD3+ cells (p=0.009) and macrophages (p=0.048) at the Day 6 timepoint. In contrast, female mice have greater numbers of TLR4 expressing CD4+ cells at all three timepoints (p=<0.001, 0.016, and <0.001 respectively), and dendritic cells at Days 3 (p=0.019) and Day 6 (p=<0.001). Numbers of mice used in this experiment were as follows: Male D6=6, D3=3, D0=3; Female D6=5, D3=4, D0=5.

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