Figure 2

Chromatogram (a) and evolutionary conservation plot (b) of a newly identified OXTR mutation, A217T, in a subject scoring on the 98th percentile for Harm Avoidance. Basewise conservation of the amplicon sequence is plotted from 5‘ to 3‘ against the physical position on chromosome 3 using 46 placental mammals featured in the UCSC Genome Browser. A217T maps to a highly conserved region encoding the 5th OXTR transmembrane domain.