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Table 1 Distribution of clinicopathological parameters in women and men

From: Modifying effect of gender on the prognostic value of clinicopathological factors and Ki67 expression in melanoma: a population-based cohort study

n (% for columns)

Female

Male

p-value

n = 132 (51.8)

n = 123 (48.2)

Age

  

0.012*

Mean

65

69

 

Median

65

70

Range

46-84

53-80

Location

  

0.001**

Dorsal trunk

20 (15.5)

45 (37.8)

 

Frontal trunk

15 (11.6)

19 (16.0)

Arms

29 (22.5)

18 (15.1)

Legs

51 (39.5)

13 (10.9)

Head and neck

14 (10.9)

24 (20.2)

Unknown

3

4

Histological type

  

0.372

SSM

80 (62.5)

80 (66.7)

 

NMM

27 (21.1)

26 (21.7)

LMM

16 (12.5)

13 (10.8)

Other

5 (3.9)

1 (0.8)

Unknown

4

3

Breslow thickness (mm)

  

0.417

Mean

1.44

1.72

 

Median

0.68

0.80

Range

(0.11-16.00)

(0.08-40.00)

Unknown

4

3

Thickness (AJCC)

  

0.180

< = 1 mm

86 (67.2)

72 (60.0)

 

1.1-2 mm

19 (14.8)

17 (14.2)

2.1-4 mm

17 (13.3)

23 (19.2)

>4 mm

6 (4.7)

8 (6.7)

Unknown

4

3

Clark level

  

0.999

II

46 (36.2)

47 (39.2)

 

III

57 (44.9)

46 (38.3)

IV

21 (16.5)

23 (19.2)

V

3 (2.4)

4 (3.3)

Unknown

5

3

Clinical stage

  

0.135

1A-B

98 (89.9)

81 (82.7)

 

2A-B

9 (8.3)

15 (15.3)

3-4

2 (1.8)

2 (2.0)

Unknown

23

25

Ulceration

  

0.962

No

111(86.0)

103 (85.8)

 

Yes

18 (14.09)

17 (14.2)

Unknown

3

3

Vascular invasion

  

0.076

No

123 (96.9)

109 (91.6)

 

Yes

4 (3.1)

10 (8.4)

Unknown

5

4

Mitotic count

  

0.769

0/mm2

69 (52.7)

62 (50.8)

 

> = 1/mm2

62 (47.3)

60 (49.2)

Unknown

3

1

Lymphocytic infiltrate

  

0.815

None-mild

38 (29.7)

34 (28.3)

 

Moderate-brisk

90 (70.3)

86 (71.7)

Unknown

4

3

Ki 67 expression

  

0.133

0-1%

4 (3.9)

11 (10.7)

 

2-25%

73 (70.9)

71 (68.9)

>25%

26 (25.2)

21 (20.4)

Unknown

29

20

Local, regional or distal recurrence

  

0.360

No

111 (84.1)

98 (79.7)

 

Yes

21 (15.9)

25 (20.3)

 

Vital status

   

Alive

114 (86.4)

88 (71.5)

 

Dead

18 (13.6)

35 (28.5)

0.004**

Dead from melanoma

9 (6.8)

19 (15.4)

0.028*

  1. The p-values refer to comparisons of male and female tumours. Mann–Whitney test for comparison of medians and Chi square test for X × 2 tables. The categories marked as not done and unknown were not included in the statistical analysis.