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Table 1 Distribution of clinicopathological parameters in women and men

From: Modifying effect of gender on the prognostic value of clinicopathological factors and Ki67 expression in melanoma: a population-based cohort study

n (% for columns) Female Male p-value
n = 132 (51.8) n = 123 (48.2)
Age    0.012*
Mean 65 69  
Median 65 70
Range 46-84 53-80
Location    0.001**
Dorsal trunk 20 (15.5) 45 (37.8)  
Frontal trunk 15 (11.6) 19 (16.0)
Arms 29 (22.5) 18 (15.1)
Legs 51 (39.5) 13 (10.9)
Head and neck 14 (10.9) 24 (20.2)
Unknown 3 4
Histological type    0.372
SSM 80 (62.5) 80 (66.7)  
NMM 27 (21.1) 26 (21.7)
LMM 16 (12.5) 13 (10.8)
Other 5 (3.9) 1 (0.8)
Unknown 4 3
Breslow thickness (mm)    0.417
Mean 1.44 1.72  
Median 0.68 0.80
Range (0.11-16.00) (0.08-40.00)
Unknown 4 3
Thickness (AJCC)    0.180
< = 1 mm 86 (67.2) 72 (60.0)  
1.1-2 mm 19 (14.8) 17 (14.2)
2.1-4 mm 17 (13.3) 23 (19.2)
>4 mm 6 (4.7) 8 (6.7)
Unknown 4 3
Clark level    0.999
II 46 (36.2) 47 (39.2)  
III 57 (44.9) 46 (38.3)
IV 21 (16.5) 23 (19.2)
V 3 (2.4) 4 (3.3)
Unknown 5 3
Clinical stage    0.135
1A-B 98 (89.9) 81 (82.7)  
2A-B 9 (8.3) 15 (15.3)
3-4 2 (1.8) 2 (2.0)
Unknown 23 25
Ulceration    0.962
No 111(86.0) 103 (85.8)  
Yes 18 (14.09) 17 (14.2)
Unknown 3 3
Vascular invasion    0.076
No 123 (96.9) 109 (91.6)  
Yes 4 (3.1) 10 (8.4)
Unknown 5 4
Mitotic count    0.769
0/mm2 69 (52.7) 62 (50.8)  
> = 1/mm2 62 (47.3) 60 (49.2)
Unknown 3 1
Lymphocytic infiltrate    0.815
None-mild 38 (29.7) 34 (28.3)  
Moderate-brisk 90 (70.3) 86 (71.7)
Unknown 4 3
Ki 67 expression    0.133
0-1% 4 (3.9) 11 (10.7)  
2-25% 73 (70.9) 71 (68.9)
>25% 26 (25.2) 21 (20.4)
Unknown 29 20
Local, regional or distal recurrence    0.360
No 111 (84.1) 98 (79.7)  
Yes 21 (15.9) 25 (20.3)  
Vital status    
Alive 114 (86.4) 88 (71.5)  
Dead 18 (13.6) 35 (28.5) 0.004**
Dead from melanoma 9 (6.8) 19 (15.4) 0.028*
  1. The p-values refer to comparisons of male and female tumours. Mann–Whitney test for comparison of medians and Chi square test for X × 2 tables. The categories marked as not done and unknown were not included in the statistical analysis.
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