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Table 1 Subjects’ anthropometric and basic metabolic characteristics at the time of screening

From: Sexually dimorphic effect of aging on skeletal muscle protein synthesis

  MEN WOMEN ANOVA
Young Old Young Old Sex Age Interaction
Age (years) 40 ± 2 69 ± 1 37 ± 2 73 ± 2 0.84 <0.001 0.10
Body mass (kg) 81 ± 4 81 ± 3 69 ± 2 61 ± 4 <0.001 0.22 0.25
Body mass index (kg/m2) 26.5 ± 1.0 25.9 ± 0.8 25.0 ± 0.8 24.0 ± 1.3 0.09 0.44 0.84
Fat mass (kg) 18 ± 2 21 ± 2 22 ± 1 23 ± 3 0.16 0.34 0.61
Fat mass (% body mass) 21 ± 2 25 ± 2 32 ± 1 36 ± 2 <0.001 0.055 0.97
Fat free mass (kg) 63 ± 2 60 ± 2 47 ± 2 38 ± 1 <0.001 0.002 0.17
Fat free mass (% body mass) 79 ± 2 75 ± 2 68 ± 1 64 ± 2 <0.001 0.055 0.97
Appendicular muscle mass (kg) 27.5 ± 1.1 24.9 ± 0.7 18.0 ± 0.9 14.1 ± 0.5 <0.001 <0.001 0.46
Appendicular muscle mass index (kg/m2) 9.0 ± 0.2 8.0 ± 0.2 6.5 ± 0.2 5.5 ± 0.2 <0.001 <0.001 0.99
Fasting plasma glucose (mg/dl) 93 ± 1 95 ± 3 87 ± 1 90 ± 1 0.005 0.18 0.54
2 h post OGTT plasma glucose (mg/dl) 94 ± 7 111 ± 8 93 ± 4 106 ± 7 0.66 0.03 0.77
HOMA-IR 1.46 ± 0.32 1.59 ± 0.27 1.08 ± 0.22 1.16 ± 0.23 0.13 0.69 0.91
Systolic blood pressure (mm Hg) 109 ± 3 119 ± 5 105 ± 3 126 ± 6 0.69 <0.001 0.21
Diastolic blood pressure (mm Hg) 69 ± 2 74 ± 3 65 ± 3 68 ± 4 0.14 0.21 0.70
Plasma triglycerides (mg/dl) 88 ± 18 102 ± 12 66 ± 8 72 ± 13 0.04 0.43 0.75
Total plasma cholesterol (mg/dl) 170 ± 10 193 ± 7 172 ± 8 197 ± 8 0.74 0.01 0.89
LDL-cholesterol (mg/dl) 106 ± 9 125 ± 6 97 ± 7 109 ± 8 0.09 0.03 0.61
HDL-cholesterol (mg/dl) 47 ± 4 49 ± 3 62 ± 4 73 ± 4 <0.001 0.09 0.25
Testosterone (ng/ml) 4.8 ± 0.5 5.7 ± 0.5 0.9 ± 0.1 0.8 ± 0.1 <0.001 0.26 0.18
Estradiol (pg/ml) 25 ± 2 18 ± 2 62 ± 9a 8 ± 3b 0.01 <0.001 <0.001
Progesterone (ng/ml) 0.24 ± 0.10 0.28 ± 0.08 5.08 ± 1.53a 0.23 ± 0.07 <0.01 <0.01 <0.01
  1. Values are means ± SEM. HOMA-IR: Homeostasis model assessment of insulin resistance. OGTT: oral glucose tolerance test.
  2. a Value significantly different from values in men and old women (P < 0.01). b Value significantly different from values in men (P < 0.05).