Figure 3
In vitro effects of androgen on coronary microvessel diameter. Percent maximal dilation of coronary resistance vessels from intact and castrated males exposed to physiologic concentrations of (a) Testosterone, (b) 5α-Dihydrotestosterone, and (c) Epitestosterone (n = 12 for intacts, n = 9 for castrates). Values are mean ± SEM. *p < 0.05 vs. baseline. The epitestosterone exposures demonstrate a main effect of castration on coronary microvessel diameter.