Figure 1
In vivo effects of androgen on the coronary circulation in anesthetized swine. Percent change in left anterior descending coronary conductance from baseline for intact and castrated males during infusions of (a) Testosterone, (b) 5α-Dihydrotestosterone and (c) Epitestosterone (n = 7-8 for intacts, n = 5-9 for castrates). Values are mean ± SEM. *p < 0.05 vs. baseline. The testosterone and 5α-dihydrotestosterone infusions demonstrate a main effect of castration on coronary conductance.