|
Treatment
|
Strain
|
CONT
|
CAST
|
CAST + T
|
|---|
|
Testosterone (ng/ml)
|
SHR
|
1.88 ± 0.52
|
0.05 ± 0.60
|
12.9 ± 0.70
|
| |
WKY
|
1.08 ± 0.52
|
0.04 ± 0.70
|
11.0 ± 0.78
|
|
Norepinephrine (pg/ml)
|
SHR
|
970.5 ± 88.4***
|
481.5 ± 50.4**
|
762.2 ± 53.8*
|
| |
WKY
|
569.5 ± 28.1
|
415.5 ± 97.3
|
644.9 ± 74.6
|
-
aCAST, castrate; CAST + T, castrate plus testosterone; CONT, control; NE, norepinephrine; SHR: spontaneously hypertensive rat; T: testosterone; WKY: Wistar Kyoto. Data are means ± SEM. Plasma T was unaltered between SHR and WKY T-manipulated groups. Plasma NE was significantly higher in SHR CONT males than in WKY CONT males (***P < 0.001). Plasma NE was decreased in SHR CAST compared to CONT (**P < 0.01) and increased compared to CAST + T (*P < 0.05).
